Differences between DNA and RNA - Class 12th Biology - Study24x7
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Differences between DNA and RNA - Class 12th Biology

Updated on 22 September 2022
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Edubabble LLP
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Updated on 22 September 2022


At the molecular level, all life has basically the same building blocks - DNA and RNA. Although DNA and RNA contain nucleotides, there are differences between DNA and RNA. So, the main difference between DNA and RNA is that DNA is double-stranded and RNA is single-stranded. DNA is responsible for providing genetic information, while RNA carries the genetic code needed to make proteins.


What is DNA?

 

DNA, or deoxyribonucleic acid, is a molecule composed of two polynucleotide chains. These molecules form an intricate double helix that carries the cellular instructions for development, function, growth and reproduction of all living things. The two strands of double-stranded DNA store the same biological information that replicates as the two strands separate.


What is RNA?

 

Ribonucleic acid RNA form is the form polymeric molecule. It contributes to various biological roles such as gene coding, decoding, regulation and expression. Messenger RNA (mRNA) in cellular organisms helps transmit genetic information that directs the synthesis of specific proteins.


What Is the Difference Between DNA and RNA?






Configuration

DNA is a two-stranded molecule made up of a long chain of nucleotides. Helix type B.

It is a single-stranded helix made up of a short nucleotide chain. A helix type.

Function

Conveys genetic information in order to create new cells and organisms. Long-term genetic information storage.

It transports the genetic code from the nucleus to the ribosomes, where it is translated into proteins.

Transmission

DNA replicates itself.

DNA-based synthesis

Composition

Backbone of deoxyribose sugar phosphate


bases of adenine, guanine, cytosine, and thymine


Sugar ribose

backbone of phosphate


bases of adenine, guanine, cytosine, and uracil


Location

Found in the nucleus and the mitochondria of a cell.

Found in the cytoplasm, nucleus, and ribosome.

Pairing and Nitrogenous Bases

GC (Guanine pairs with Cytosine) A-T(Adenine pairs with Thymine).

A-U (Adenine pairs with Uracil) GC (Guanine pairs with Cytosine)

Molecular Mass

Between 2 and 6 million

25,000 to 2,000,000

Stability

DNA has a higher stability than RNA. Under alkaline conditions, DNA is stable.

It is much more reactive than DNA and is unstable in alkaline environments.

Sensitivity to Ultraviolet (UV)

UV light has the potential to damage DNA.

Much more immune to UV light damage than DNA.



DNA


DNA, also known as deoxyribonucleic acid, serves as the initial blueprint for protein production in cells. Deoxyribose, phosphates, and a specific arrangement of the nitrogenous bases adenine (A), guanine (G), cytosine (C), and thymine are all found in DNA (T).


A brief overview of the structure and composition of DNA 

 

 DNA molecules contain the instructions organisms need to grow, develop and reproduce. These instructions are contained within each cell and are passed on by parents to their children.


They are nucleotides that contain one nitrogen, one phosphate, and one sugar. The sequence of nitrogenous bases - thymine (T), guanine (G), cytosine (C) and adenine (A), is very important in determining the genetic code.


Genes are made up of nitrogenous bases in DNA that are essential for protein synthesis. RNA is another nucleic acid that translates genetic information into proteins from DNA.


Nucleotides are joined together to form two long strands that move in a circle to form a structure known as a double helix that resembles a layer of sugar and phosphate molecules that form side by side. make the trap come from the foundation.

 

 Dependence on one of the two strands has a base on the other strand, as in pairs - guanine and cytosine and adenine and thymine. DNA molecules are very long, so without proper packaging, they cannot enter cells.


As a result, the DNA is tightly linked to form structures called chromosomes. Each chromosome contains one DNA molecule. In humans, 23 pairs of chromosomes are located in the nucleus of the cell.


DNA Types


A-DNA: At a relative humidity of 75%, it can be discovered. It survives in a form that contains 11 nucleotide pairs with an increase of 2.56 vertically per base pair in environments with greater salt concentrations or ionic concentrations, such as K+, Na+, or Cs+, or in a state of dryness. Among all DNA forms, 23 DNA, a typical helix with a right-handed rotation of 32.70 degrees per base pair, has the largest helical diameter.


B-DNA: The most prevalent type, found in the majority of DNA at physiological salt concentrations and pH neutrality. Per round around the helix axis, there are ten base pairs.

The helical diameter is 20 and the distance is 3.4. As a B-form of DNA, Watson-double Crick's helix model is known.


C-DNA: It is found in the presence of a few ions, such as lithium(Li+), and with a relative humidity of 66%. 9.33 base pairs are present on each turn. The right-handed helix has a diameter of around 19 and a vertical rise for each base pair of 3.320.


D-DNA: It is an uncommon extreme variant that is observed. With an axial rise of approximately 3.03, the 8 base pairs are inclined negatively from the helix axis.


Z-DNA: It can be discovered in environments with a lot of salt. It has a left-handed helical structure, in contrast to DNA types A, B, and C. The sugar-phosphate bond creates a zigzag pattern in the backbone, with the dinucleotide as the recurrent monomer as opposed to the mononucleotide, which is seen in alternate forms.


RNA


A nucleic acid directly involved in the production of proteins is ribonucleic acid (RNA). All living cells include the significant nucleotide ribonucleic acid, which is found in long chains. Its primary function is to serve as a messenger, carrying DNA's instructions for regulating protein synthesis.


Ribose, phosphates, and the nitrogenous bases adenine (A), guanine (G), cytosine (C), and uracil are all found in RNA (U). The nitrogenous bases A, G, and C are shared by DNA and RNA. Uracil and thymine are often only found in DNA and RNA, respectively.


Variety Of RNA


Only some of a cell's genes are translated into RNA. The types of RNA that are each represented by a distinct gene type are as follows:



  1. tRNA: During translation, the transfer RNA (tRNA) transports amino acids to ribosomes.
  2. The messenger RNA, or mRNA, encodes a polypeptide's amino acid sequences.
  3. mRNA is translated into protein-containing organelles called ribosomes by the ribosomal proteins that are produced by the ribosomal RNA, or rRNA.
  4. Small nuclear RNA (snRNA) joins forces with proteins to form complexes that are used by eukaryotes to digest RNA.


Protein's Function


Remember that some proteins are enzymes that support cells by catalyzing chemical reactions in order to put these concepts into the right perspective. After the enzyme binds its substrate at the active site, these chemical processes take place. The size, shape, and chemical characteristics of the substrate molecule match those of the active site of the enzyme.


The combination of the enzyme's individual amino acids, which make up the enzyme's subunits, determines the size, structure, and chemical characteristics of the active site of an enzyme. The arrangement of amino acids in a protein during the synthesis of an enzyme must be under the control of the cell in order for the cell to consistently produce an enzyme.


Cells' ability to successfully deal with the demands of life depends heavily on proteins. Proteins are used by cells to keep their form and to hasten vital chemical processes like respiration and photosynthesis.


If a cell can't consistently produce the proteins it needs to survive, it won't live very long.


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